Current projectReview

Research using neural organoids

Assessing and advising on the ethical and regulatory issues raised by research using neural organoids.

Organoids are small, lab-grown three-dimensional structures that are made from stem cells to model different aspects of an organ or tissue. Neural organoids are used to model different aspects of the developing brain.

In March 2024 we published a briefing note offering an evidence-based and balanced summary of the main ethical considerations in neural organoid research and the ethical issues that might arise in the future.

Invitation to tender

We are commissioning a comparative mapping exercise to identify and synthesise governance mechanisms as relevant to the creation, storage and use of neural organoids, assembloids and other, similar models. The findings from this exercise will be included within our forthcoming publication on neural organoids.

Find out more about the opportunity and how to apply here.

Applications close at 5pm on 28 August 2025.

Call for evidence (closed)

From July – September 2024 we ran a call for evidence seeking expert opinion on the three key areas where we believe further ethical guidance is needed:

• How regulation and governance of neural organoids can be proportionate and future proofed.
• What an informed consent process, able to account for fast-paced developments and an unpredictable direction of research, could look like.
• What current and possible future characteristics of neural organoids could have implications for their moral and legal significance, and so may warrant special ethical consideration.

This call for evidence is now closed, but if you would like to contribute to the project we would be pleased to hear from you, please contact Claudia Corradi.