Current projectReview

Reviewing the 14-day rule for human embryo research

Exploring arguments for and against extending the 14-day time limit for human embryo research. 

The Human Fertilisation and Embryology (HFE) Act 1990 (as amended in 2008) states that human embryos can only be cultured in a UK laboratory for a maximum of 14 days, a rule that has been adopted in many jurisdictions worldwide. However, human embryo research has advanced in recent years, its potential now raising questions around whether the 14-day time limit should be extended.

We are undertaking a project to explore the current and future ethical, scientific, social, and policy considerations related to the 14-day rule for human embryo research, with the aim of informing UK legislative reform. The project activities will take place across four phases, overseen and guided by a multidisciplinary working group.

• Phase 1: Review of the short-, medium- and long-term potential of the science of human embryo research, including future scenario mapping. 
• Phase 2: Review of the ethics of human embryo research, including future scenario mapping. 
• Phase 3: UK-based deliberative dialogue to understand public views and values surrounding human embryo research and its limits.  
• Phase 4: Review of evidence gathered in phases 1-3 and deliberation of different policy options that take into account trade-offs, stakeholder and public attitudes, and the international research landscape. 

This project is funded by a grant from Wellcome.