13 Mar 2023
The available methods of human heritable genome editing are not yet considered safe enough for clinical use, but the three councils wish to ensure that before they reach this point more attention is given to fundamental ethical questions and principles. Only in this way can global dialogue and governance of heritable genome editing proceed on sound ethical grounds.
In a letter published in Naturetoday, the Chairs of the three Councils, each of which has produced its own report on genome editing, highlight these key points from the joint statement:
“We call on governments and stakeholders around the world to take the following action:
We all consider it essential that any ethically permissible application of human genome editing should not increase disadvantage, discrimination or division in society.
The large range of conceivable applications and their implications for families, society and future generations, calls for appropriate, cautious, responsible and transparent governance.
We encourage all participants in debates around heritable genome editing and the respective decision makers to reflect on the examples of ethical deliberation provided in our individual reports.”
Notes to Editors
The joint statement is published at:
The Correspondence published in Nature will be available from 10am UK time on Tuesday 3 March at: https://www.nature.com/nature/articles?type=correspondence
Full publications of the three Councils are as follows:
In France, Germany and the UK heritable genome editing is prohibited by law, but the situation is different in other jurisdictions, where the rules may be unclear, unenforced, or non-existent. Despite widespread condemnation of the actions of a Chinese researcher whose work resulted in the birth of genome edited twins in 2018, other scientists have already announced plans to attempt heritable human genome editing.
Marie-Christine Simon, CCNE
Email: email@example.com / Tel: +33 1 42 75 68 29
Ulrike Florian, Deutscher Ethikrat
Email: firstname.lastname@example.org / Tel: +49 30 203 70-246
Sarah Walker-Robson, Nuffield Council on Bioethics
Email: email@example.com / Tel: +44 (0)20 7681 9619